How we achieve NEPTUNE's goals
Why use the precision medicine approach to treat patients with kidney disease?
Instead of “one size fits all” treatments, precision medicine uses personalized care by taking into account the individuality of the patient and the underlying cause of theirdisease. Using a personalized medicaltreatment that considers this underlying biology, or cause, of a person’sdisease achieves the best outcomes.
NEPTUNE Match is our newest study that gives participants information about which clinical trials may be a “match” to them by using their individual research data and samples collected from the NEPTUNE study.
NEPTUNE strives to match participants to clinical trials because we know that even if two people have the same diagnosis and are suffering from the same symptoms, what is causing the disease in one person may be different than what is causing the disease in another.
NEPTUNE Match takes individual participant data from their participation in the NEPTUNE study to better understand what is causing their kidney disease and attempts to share how they match to participating clinical trials.
Because different clinical trials offer different treatments, some of the treatments offered may better target the underlying biology, or cause, of the participant’s kidney disease.
NEPTUNE is a multi-center consortium led by Matthias Kretzler, MD, University of Michigan. The network includes:
NEPTUNE is a member of the Rare Disease Clinical Research Network (RDCRN). The RDCRN is designed to advance medical research on rare diseases by providing support for clinical studies and facilitating collaboration, study enrollment and data sharing.
The DACC is responsible for generating and analyzing data, supporting collaborative research, and providing the organizational and scientific support for the full NEPTUNE consortium.
Enrollment sites are responsible for recruiting study participants with nephrotic syndrome and Alport syndrome and for conducting study visits according to the protocol.
The ancillary studies/pilot program is responsible for facilitating scientific use of NEPTUNE data, biospecimens, biopsy slide images, and infrastructure.
The career enhancement program is responsible for the NEPTUNE fellowship funding mechanism and for opportunities for junior investigators to develop research skills in glomerular science.